Short-interval exposure to ambient fine particulate matter (PM2.5) exacerbates the susceptibility of pulmonary damage in setting of lung ischemia-reperfusion injury in rodent: Pharmacomodulation of melatonin

Short-interval exposure to ambient fine particulate matter (PM2.5) exacerbates the susceptibility of pulmonary damage in setting of lung ischemia-reperfusion injury in rodent: Pharmacomodulation of melatonin

This study tested the hypothesis that exposure to ambient fine particulate matter (PM2.5) pollution increased susceptibility of rat lung to damage from acute ischemia-reperfusion (IR) injury that was reversed by melatonin (Mel) treatment. Male-adult SD rats (n = 30) were categorized into group 1 (no...

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Bibliographic Details
Main Authors: Fan-Yen Lee, Mel S. Lee, Christopher Glenn Wallace, Chi-Ruei Huang, Chi-Hsiang Chu, Zhi-Hong Wen, Jhih-Hong Huang, Xue-Sheng Chen, Chia C. Wang, Hon-Kan Yip
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Acute exposure of PM2.5
Lung parenchymal damage
Inflammation
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219302410

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http://www.sciencedirect.com/science/article/pii/S0753332219302410

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