The Role of the Carnitine/Organic Cation Transporter Novel 2 in the Clinical Outcome of Patients With Locally Advanced Esophageal Carcinoma Treated With Oxaliplatin

The Role of the Carnitine/Organic Cation Transporter Novel 2 in the Clinical Outcome of Patients With Locally Advanced Esophageal Carcinoma Treated With Oxaliplatin

Esophageal cancer is the ninth most common malignancy worldwide, ranking sixth in mortality. Platinum-based chemotherapy is commonly used for treating locally advanced esophageal cancer, yet it is ineffective in a large portion of patients. There is a need for reliable molecular markers with direct...

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Bibliographic Details
Main Authors: Dongfeng Sun, Qingfa Chen, Zhibo Gai, Fengxia Zhang, Xiaoqing Yang, Wensi Hu, Chengyu Chen, Guangjie Yang, Severin Hörmann, Gerd. A. Kullak-Ublick, Michele Visentin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
biomarker
carnitine transporter
esophageal cancer
oxaliplatin
OCTN2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.684545/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.684545/full

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