T‐cell receptor repertoire analysis for the diagnosis and treatment of solid tumor: A methodology and clinical applications

Abstract T cells, which are involved in adaptive immunity, are essential in the elimination of tumor cells. Mature T cells can specifically recognize the antigen on the major histocompatibility complex (MHC) molecule through T‐cell receptors (TCR). The unique rearrangement mechanisms during T‐cell m...

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Bibliographic Details
Main Authors: Na Li, Jiani Yuan, Wenjia Tian, Lin Meng, Yongyu Liu
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Cancer Communications
Subjects:
Online Access:https://doi.org/10.1002/cac2.12074