Integrated genomic and transcriptomic analysis revealed mutation patterns of de-differentiated liposarcoma and leiomyosarcoma

Integrated genomic and transcriptomic analysis revealed mutation patterns of de-differentiated liposarcoma and leiomyosarcoma

Abstract Background Treating patients with advanced sarcomas is challenging due to great histologic diversity among its subtypes. Leiomyosarcoma (LMS) and de-differentiated liposarcoma (DDLPS) are two common and aggressive subtypes of soft tissue sarcoma (STS). They differ significantly in histology...

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Bibliographic Details
Main Authors: Wenshuai Liu, Hanxing Tong, Chenlu Zhang, Rongyuan Zhuang, He Guo, Chentao Lv, Hua Yang, Qiaowei Lin, Xi Guo, Zhiming Wang, Yan Wang, Feng Shen, Shengzhou Wang, Chun Dai, Guan Wang, Jun Liu, Weiqi Lu, Yong Zhang, Yuhong Zhou
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Cancer
Subjects:
Soft tissue sarcoma
Gene fusion
Tumor microenvironment
Immune infiltration
Online Access:http://link.springer.com/article/10.1186/s12885-020-07456-2

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http://link.springer.com/article/10.1186/s12885-020-07456-2

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