Impacts of CR1 genetic variants on cerebrospinal fluid and neuroimaging biomarkers in alzheimer’s disease

Abstract Background The complement component (3b/4b) receptor 1 gene (CR1) gene has been proved to affect the susceptibility of Alzheimer’s disease (AD) in different ethnic and districts groups. However, the effect of CR1 genetic variants on amyloid β (Aβ) metabolism of AD human is still unclear. He...

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Bibliographic Details
Main Authors: Xi-chen Zhu, Wen-zhuo Dai, Tao Ma
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Medical Genetics
Subjects:
CR1
Online Access:http://link.springer.com/article/10.1186/s12881-020-01114-x