Site-Specific Labeling of scVEGF with Fluorine-18 for Positron Emission Tomography Imaging

<p>Vascular endothelial growth factor (VEGF) is one of the most important mediators of angiogenesis. Single-chain (sc)-VEGF protein containing an N-terminal Cys-tag has been designed for site-specific modification with a variety of imaging and therapeutic moieties. Site-specific labeling of sc...

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Bibliographic Details
Main Author: Hui Wang, Haokao Gao, Ning Guo, Gang Niu, Ying Ma, Dale O. Kiesewetter, Xiaoyuan Chen
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:Theranostics
Online Access:http://www.thno.org/v02p0607.htm