Effects of AS-cast and wrought cobalt-chrome-molybdenum and titanium-aluminium-vanadium alloys on cytokine gene expression and protein secretion in J774A.1 macrophages

Insertion of metal implants is associated with a possible change in the delicate balance between pro- and anti-inflammatory proteins, probably leading to an unfavourable predominantly pro-inflammatory milieu. The most likely cause is an inappropriate activation of macrophages in close relation to th...

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Bibliographic Details
Main Authors: S S Jakobsen, A Larsen, M Stoltenberg, J M Bruun, K Soballe
Format: Article
Language:English
Published: AO Research Institute Davos 2007-09-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/journal/papers/vol014/pdf/v014a05.pdf