Effect of amiloride: An Na + / H + exchange inhibitor in the middle cerebral artery occlusion model of focal cerebral ischemia in rats

Purpose : The effect of pretreatment with amiloride (AML), an Na + / H + exchange inhibitor was studied in the middle cerebral artery occlusion (MCAO) model of focal cerebral ischemia in rats. Materials and Methods : Male wistar rats were subjected to 2 hr of MCAO followed by 22-hr reperfusion. Grip...

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Bibliographic Details
Main Authors: Mohammad Akhtar, K K Pillai, Abul Kalam Najmi, Divya Vohora
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2011;volume=3;issue=4;spage=519;epage=524;aulast=Akhtar