Novel hybrid polyester-polyacrylate hydrogels enriched with platelet-derived growth factor for chondrogenic differentiation of adipose-derived mesenchymal stem cells in vitro

Novel hybrid polyester-polyacrylate hydrogels enriched with platelet-derived growth factor for chondrogenic differentiation of adipose-derived mesenchymal stem cells in vitro

Abstract Background The goal of the present study was to create a new biodegradable hybrid PCL-P (HEMA-NIPAAm) thermosensitive hydrogel scaffold by grafting PNIPAAm-based copolymers with biodegradable polyesters to promote the chondrogenic differentiation of human progenitor cells (adipose-derived s...

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Bibliographic Details
Main Authors: Fereshteh Valipour, Farzaneh Valipour, Reza Rahbarghazi, Amir Mohammad Navali, Mohammad Reza Rashidi, Soodabeh Davaran
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Biological Engineering
Subjects:
Nanostructured scaffold
Thermosensitive hydrogel
Adipose-derived stem cells
Chondrogenesis
Online Access:https://doi.org/10.1186/s13036-021-00257-6

Internet

https://doi.org/10.1186/s13036-021-00257-6

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