Umbilical cord-derived CD362+ mesenchymal stromal cells for E. coli pneumonia: impact of dose regimen, passage, cryopreservation, and antibiotic therapy

Abstract Background Mesenchymal stromal cells (MSCs) demonstrate considerable promise for acute respiratory distress syndrome (ARDS) and sepsis. However, standard approaches to MSC isolation generate highly heterogeneous cell populations, while bone marrow (BM) constitutes a limited and difficult to...

Full description

Bibliographic Details
Main Authors: Shahd Horie, Claire Masterson, Jack Brady, Paul Loftus, Emma Horan, Lisa O’Flynn, Steve Elliman, Frank Barry, Timothy O’Brien, John G. Laffey, Daniel O’Toole
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-020-01624-8