D-Serine: A Cross Species Review of Safety

Background:D-Serine, a direct, full agonist at the D-serine/glycine modulatory site of the N-methyl-D-aspartate-type glutamate receptors (NMDAR), has been assessed as a treatment for multiple psychiatric and neurological conditions. Based on studies in rats, concerns of nephrotoxicity have limited D...

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Bibliographic Details
Main Authors: Amir Meftah, Hiroshi Hasegawa, Joshua T. Kantrowitz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.726365/full