Newcastle Disease Virus Nonstructural V Protein Upregulates SOCS3 Expression to Facilitate Viral Replication Depending on the MEK/ERK Pathway

Newcastle Disease Virus Nonstructural V Protein Upregulates SOCS3 Expression to Facilitate Viral Replication Depending on the MEK/ERK Pathway

Newcastle disease virus (NDV) causes serious economic losses to the poultry industry. In our previous study, we found that NDV induced a strong innate immune response in the chicken embryo and bursa of Fabricius (BF). However, the underlying mechanisms by which NDV escapes the host innate immunity a...

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Bibliographic Details
Main Authors: Xiangwei Wang, Yanqing Jia, Juan Ren, Na Huo, Haijin Liu, Sa Xiao, Xinglong Wang, Zengqi Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Newcastle disease virus
SOCS3
V protein
MEK/ERK pathway
viral replication
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00317/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00317/full

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