Phytanic acid is ligand and transcriptional activator of murine liver fatty acid binding protein

Phytanic acid is ligand and transcriptional activator of murine liver fatty acid binding protein

Branched-chain phytanic acid is metabolized in liver peroxisomes. Sterol carrier protein 2/sterol carrier protein x (SCP2/SCPx) knockout mice, which develop a phenotype with a deficiency in phytanic acid degradation, accumulate dramatically high concentrations of this fatty acid in serum (Seedorf at...

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Bibliographic Details
Main Authors: Christian Wolfrum, Peter Ellinghaus, Manfred Fobker, Udo Seedorf, Gerd Assmann, Torsten Börchers, Friedrich Spener
Format: Article
Language:English
Published: Elsevier 1999-04-01
Series:Journal of Lipid Research
Subjects:
peroxisome proliferator-activated receptor
peroxisome proliferation
sterol carrier protein 2
sterol carrier protein x
isothermal titration calorimetry
SCP2/SCPx-deficient knock out mice
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520321507

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http://www.sciencedirect.com/science/article/pii/S0022227520321507

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