Evaluation of the biocompatibility and stability of allogeneic tissue-engineered cartilage in humanized mice.

Articular cartilage (AC) has poor capacities of regeneration and lesions often lead to osteoarthritis. Current AC reconstruction implies autologous chondrocyte implantation which requires tissue sampling and grafting. An alternative approach would be to use scaffolds containing off-the-shelf allogen...

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Bibliographic Details
Main Authors: Emeline Perrier-Groult, Eléonore Pérès, Marielle Pasdeloup, Louis Gazzolo, Madeleine Duc Dodon, Frédéric Mallein-Gerin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217183