miR-181a-regulated pathways in T-cell differentiation and aging

Abstract MicroRNAs (miRNAs) are regulatory noncoding RNAs important for many aspects of cellular processes including cell differentiation and proliferation. Functions of numerous miRNAs have been identified in T cells, with miR-181a regulating T cell activation thresholds during thymic T cell develo...

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Bibliographic Details
Main Authors: Chulwoo Kim, Zhongde Ye, Cornelia M. Weyand, Jörg J. Goronzy
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-021-00240-1