Protective unfolded protein response in human pancreatic beta cells transplanted into mice.

There is great interest about the possible contribution of ER stress to the apoptosis of pancreatic beta cells in the diabetic state and with islet transplantation.Expression of genes involved in ER stress were examined in beta cell enriched tissue obtained with laser capture microdissection (LCM) f...

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Bibliographic Details
Main Authors: Jeffrey Kennedy, Hitoshi Katsuta, Min-Ho Jung, Lorella Marselli, Allison B Goldfine, Ulysses J Balis, Dennis Sgroi, Susan Bonner-Weir, Gordon C Weir
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2887848?pdf=render