Candidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profiling.

Candidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profiling.

Breast cancers (BCs) of the luminal B subtype are estrogen receptor-positive (ER+), highly proliferative, resistant to standard therapies and have a poor prognosis. To better understand this subtype we compared DNA copy number aberrations (CNAs), DNA promoter methylation, gene expression profiles, a...

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Bibliographic Details
Main Authors: Stéphanie Cornen, Arnaud Guille, José Adélaïde, Lynda Addou-Klouche, Pascal Finetti, Marie-Rose Saade, Marwa Manai, Nadine Carbuccia, Ismahane Bekhouche, Anne Letessier, Stéphane Raynaud, Emmanuelle Charafe-Jauffret, Jocelyne Jacquemier, Salvatore Spicuglia, Hugues de The, Patrice Viens, François Bertucci, Daniel Birnbaum, Max Chaffanet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3886975?pdf=render

Internet

http://europepmc.org/articles/PMC3886975?pdf=render

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