Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation.

Both nature and induced regulatory T (Treg) lymphocytes are potent regulators of autoimmune and allergic disorders. Defects in endogenous Treg cells have been reported in patients with allergic asthma, suggesting that disrupted Treg cell-mediated immunological regulation may play an important role i...

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Bibliographic Details
Main Authors: Wei Xu, Qin Lan, Maogen Chen, Hui Chen, Ning Zhu, Xiaohui Zhou, Julie Wang, Huimin Fan, Chun-Song Yan, Jiu-Long Kuang, David Warburton, Dieudonnée Togbe, Bernhard Ryffel, Song-Guo Zheng, Wei Shi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3392250?pdf=render