Severe and persistent depletion of circulating plasmacytoid dendritic cells in patients with 2009 pandemic H1N1 infection.

BACKGROUND: Dysregulation of host immune responses plays a critical role in the pathogenesis of severe 2009 pandemic H1N1 infection. Whether H1N1 virus could escape innate immune defense in vivo remains to be investigated. The aim of this study was to evaluate the pattern of innate immune response d...

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Main Authors: Miriam Lichtner, Claudio M Mastroianni, Raffaella Rossi, Gianluca Russo, Valeria Belvisi, Raffaella Marocco, Claudia Mascia, Cosmo Del Borgo, Fabio Mengoni, Ilaria Sauzullo, Gabriella d'Ettorre, Claudia D'Agostino, Anna P Massetti, Vincenzo Vullo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3098245?pdf=render