Molecular Mechanisms Directing Migration and Retention of Natural Killer Cells in Human Tissues

A large body of data shows that Natural Killer (NK) cells are immune effectors exerting a potent cytolytic activity against tumors and virus infected cells. The discovery and characterization of several inhibitory and activating receptors unveiled most of the mechanisms allowing NK cells to spare he...

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Bibliographic Details
Main Authors: Roberta Castriconi, Paolo Carrega, Alessandra Dondero, Francesca Bellora, Beatrice Casu, Stefano Regis, Guido Ferlazzo, Cristina Bottino
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02324/full