Mechanisms involved in follistatin‐induced hypertrophy and increased insulin action in skeletal muscle

Mechanisms involved in follistatin‐induced hypertrophy and increased insulin action in skeletal muscle

Abstract Background Skeletal muscle wasting is often associated with insulin resistance. A major regulator of muscle mass is the transforming growth factor β (TGF‐β) superfamily, including activin A, which causes atrophy. TGF‐β superfamily ligands also negatively regulate insulin‐sensitive proteins,...

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Bibliographic Details
Main Authors: Xiuqing Han, Lisbeth Liliendal Valbjørn Møller, Estelle De Groote, Kirstine Nyvold Bojsen‐Møller, Jonathan Davey, Carlos Henríquez‐Olguin, Zhencheng Li, Jonas Roland Knudsen, Thomas Elbenhardt Jensen, Sten Madsbad, Paul Gregorevic, Erik Arne Richter, Lykke Sylow
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Muscle wasting
Follistatin
TGF‐β
Glucose uptake
Insulin resistance
Glycaemic control
Online Access:https://doi.org/10.1002/jcsm.12474

Internet

https://doi.org/10.1002/jcsm.12474

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