Investigating Immunization With Nucleotide Enzymes of Schistosoma mansoni: Nucleoside Diphosphate Kinase and Adenylosuccinate Lyase as New Antigenic Targets Against Schistosomiasis

Investigating Immunization With Nucleotide Enzymes of Schistosoma mansoni: Nucleoside Diphosphate Kinase and Adenylosuccinate Lyase as New Antigenic Targets Against Schistosomiasis

Schistosomiasis, caused by Schistosoma mansoni trematode worm, affects more than 1.5 million people in Brazil. The current treatment consists in the administration of Praziquantel, the only medicine used for treatment for more than 40 years. Some of the limitations of this drug consist in its inacti...

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Main Authors: Túlio di Orlando Cagnazzo, Camila Tita Nogueira, Cynthia Aparecida de Castro, Débora Meira Neris, Ana Carolina Maragno Fattori, Ricardo de Oliveira Correia, Yulli Roxenne Albuquerque, Bruna Dias de Lima Fragelli, Tiago Manuel Fernandes Mendes, Silmara Marques Allegretti, Edson Garcia Soares, Larissa Romanello, Juliana Roberta Torini, Humberto D’Muniz Pereira, Fernanda de Freitas Anibal
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
schistosomiasis
Schistosoma mansoni
Nucleoside Diphosphate Kinase
Adenylosuccinate Lyase
immunization
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.569988/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.569988/full

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