Confocal Spectroscopy to Study Dimerization, Oligomerization and Aggregation of Proteins: A Practical Guide

Confocal Spectroscopy to Study Dimerization, Oligomerization and Aggregation of Proteins: A Practical Guide

Protein self-association is a key feature that can modulate the physiological role of proteins or lead to deleterious effects when uncontrolled. Protein oligomerization is a simple way to modify the activity of a protein, as the modulation of binding interfaces allows for self-activation or inhibiti...

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Bibliographic Details
Main Authors: Yann Gambin, Mark Polinkovsky, Bill Francois, Nichole Giles, Akshay Bhumkar, Emma Sierecki
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:International Journal of Molecular Sciences
Subjects:
single molecule spectroscopy
number and brightness analysis
protein folding
protein oligomerization
protein-protein interactions
Online Access:http://www.mdpi.com/1422-0067/17/5/655

Internet

http://www.mdpi.com/1422-0067/17/5/655

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