Stress-Induced Reduction of Dorsal Striatal D2 Dopamine Receptors Prevents Retention of a Newly Acquired Adaptive Coping Strategy

Stress-Induced Reduction of Dorsal Striatal D2 Dopamine Receptors Prevents Retention of a Newly Acquired Adaptive Coping Strategy

The inability to learn an adaptive coping strategy in a novel stressful condition leads to dysfunctional stress coping, a marker of mental disturbances. This study tested the involvement of dorsal striatal dopamine receptors in the dysfunctional coping with the Forced Swim test fostered by a previou...

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Bibliographic Details
Main Authors: Paolo Campus, Sonia Canterini, Cristina Orsini, Maria Teresa Fiorenza, Stefano Puglisi-Allegra, Simona Cabib
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Pharmacology
Subjects:
dopamine receptors
dorsolateral striatum
helplessness behavior
hemispheric bias
memory consolidation
sustained threat
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00621/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00621/full

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