Inhibition of human squalene monooxygenase by tellurium compounds: evidence of interaction with vicinal sulfhydryls
Squalene monooxygenase is a flavin adenine dinucleotide-containing, microsomal enzyme that catalyzes the second step in the committed pathway for cholesterol biosynthesis. Feeding weanling rats a diet containing 1% elemental tellurium causes a transient, peripheral demyelination due to the disruptio...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2001-02-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520316849 |