C5-Azobenzene-substituted 2'-Deoxyuridine-containing Oligodeoxynucleotides for Photo-Switching Hybridization

C5-Azobenzene-substituted 2'-Deoxyuridine-containing Oligodeoxynucleotides for Photo-Switching Hybridization

A new photoisomeric nucleoside dUAz bearing an azobenzene group at the C5-position of 2'-deoxyuridine was designed and synthesized. Photoisomerization of dUAz in oligodeoxynucleotides can be achieved rapidly and selectively with 365 nm (forward) and 450 nm (backward) irradiation. Thermal denat...

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Bibliographic Details
Main Authors: Shohei Mori, Kunihiko Morihiro, Satoshi Obika
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Molecules
Subjects:
azobenzene
molecular switch
nucleoside
oligonucleotide
photochromism
Online Access:http://www.mdpi.com/1420-3049/19/4/5109

Internet

http://www.mdpi.com/1420-3049/19/4/5109

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