The N-reductive system composed of mitochondrial amidoxime reducing component (mARC), cytochrome b5 (CYB5B) and cytochrome b5 reductase (CYB5R) is regulated by fasting and high fat diet in mice.

The mitochondrial amidoxime reducing component mARC is the fourth mammalian molybdenum enzyme. The protein is capable of reducing N-oxygenated structures, but requires cytochrome b5 and cytochrome b5 reductase for electron transfer to catalyze such reactions. It is well accepted that the enzyme is i...

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Main Authors: Heyka H Jakobs, Michal Mikula, Antje Havemeyer, Adriana Strzalkowska, Monika Borowa-Chmielak, Artur Dzwonek, Marta Gajewska, Ewa E Hennig, Jerzy Ostrowski, Bernd Clement
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4140751?pdf=render