Survival of salivary gland cancer stem cells requires mTOR signaling

Abstract Advanced salivary gland mucoepidermoid carcinoma (MEC) is a relentless cancer that exhibits resistance to conventional chemotherapy. As such, treatment for patients with advanced MEC is tipically radical surgery and radiotherapy. Facial disfigurement and poor quality of life are frequent tr...

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Bibliographic Details
Main Authors: Nathalia P. Andrade, Kristy A. Warner, Zhaocheng Zhang, Alexander T. Pearson, Andrea Mantesso, Douglas M. Guimaraēs, Albina Altemani, Fernanda V. Mariano, Fabio D. Nunes, Jacques E. Nör
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03391-7