A Strategy for Personalized Treatment of iPS-Retinal Immune Rejections Assessed in Cynomolgus Monkey Models

A Strategy for Personalized Treatment of iPS-Retinal Immune Rejections Assessed in Cynomolgus Monkey Models

Recently, we successfully transplanted an autograft, or major histocompatibility complex (MHC)-matched allografts, from induced-pluripotent-stem-cell-derived retinal pigment epithelial (iPSC-RPE) cells in patients with age-related macular degeneration. However, there was an issue regarding immune re...

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Bibliographic Details
Main Authors: Shota Fujii, Sunao Sugita, Yoko Futatsugi, Masaaki Ishida, Ayaka Edo, Kenichi Makabe, Hiroyuki Kamao, Yuko Iwasaki, Hirokazu Sakaguchi, Yasuhiko Hirami, Yasuo Kurimoto, Masayo Takahashi
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
iPS cells
retinal pigment epithelial cells
immune rejection
drug
transplantation
Online Access:https://www.mdpi.com/1422-0067/21/9/3077

Internet

https://www.mdpi.com/1422-0067/21/9/3077

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