Boosting heritability: estimating the genetic component of phenotypic variation with multiple sample splitting

Abstract Background Heritability is a central measure in genetics quantifying how much of the variability observed in a trait is attributable to genetic differences. Existing methods for estimating heritability are most often based on random-effect models, typically for computational reasons. The al...

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Bibliographic Details
Main Authors: The Tien Mai, Paul Turner, Jukka Corander
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-021-04079-7