Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition

Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition

Abstract Background The disco-interacting protein 2 homolog C (DIP2C) gene is an uncharacterized gene found mutated in a subset of breast and lung cancers. To understand the role of DIP2C in tumour development we studied the gene in human cancer cells. Methods We engineered human DIP2C knockout cell...

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Bibliographic Details
Main Authors: Chatarina Larsson, Muhammad Akhtar Ali, Tatjana Pandzic, Anders M. Lindroth, Liqun He, Tobias Sjöblom
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Cancer
Subjects:
Cancer
DIP2C
Gene knockout
rAAV-mediated gene targeting
Tumour cell biology
DNA methylation
Online Access:http://link.springer.com/article/10.1186/s12885-017-3472-5

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http://link.springer.com/article/10.1186/s12885-017-3472-5

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