Effects of caffeine or RX821002 in rats with a neonatal ventral hippocampal lesion

Effects of caffeine or RX821002 in rats with a neonatal ventral hippocampal lesion

Rats with a neonatal ventral hippocampal lesion (NVHL) are used to model schizophrenia. They show enhanced locomotion and difficulties in learning after puberty. Such behavioural modifications are strengthened by dopaminergic psychostimulant drugs, which is also relevant for schizophrenia because il...

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Bibliographic Details
Main Authors: Guy eSandner, Marie-Josée eAngst, Thierry eGuiberteau, Blandine eGuignard, Astrid eNehlig
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Dopamine
Xanthine
Brain Development
noradrenaline
Animal model of schizophrenia
neonatal ventral hippocampal lesion
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00015/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00015/full

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