Dok2 mediates the CD200Fc attenuation of Aβ-induced changes in glia

<p>Abstract</p> <p>Background</p> <p>The interaction between the membrane glycoprotein, CD200 and its cognate receptor CD200 receptor (CD200R), has been shown to play a role in maintaining microglia in a quiescent state. There is evidence of increased activation under r...

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Bibliographic Details
Main Authors: Lyons Anthony, Downer Eric J, Costello Derek A, Murphy Niamh, Lynch Marina A
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://www.jneuroinflammation.com/content/9/1/107