Extracellular vesicles-mediated signaling in the osteosarcoma microenvironment: Roles and potential therapeutic targets

Osteosarcoma (OS) is the most common non-hematologic malignant tumor of bone in children. It is usually characterized by a high risk of developing lung metastasis and poor prognosis. Extracellular vesicles (EVs) are cell-derived nanoparticles with a small size of 50–200 nm in diameter. As a communic...

Full description

Bibliographic Details
Main Authors: Min Lan, Xiao-Ping Zhu, Zhi-Yuan Cao, Jia-Ming Liu, Qing Lin, Zhi-Li Liu
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Journal of Bone Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137418300101