Genome-wide association study of gene by smoking interactions in coronary artery calcification.

Genome-wide association study of gene by smoking interactions in coronary artery calcification.

Many GWAS have identified novel loci associated with common diseases, but have focused only on main effects of individual genetic variants rather than interactions with environmental factors (GxE). Identification of GxE interactions is particularly important for coronary heart disease (CHD), a major...

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Bibliographic Details
Main Authors: Linda M Polfus, Jennifer A Smith, Lawrence C Shimmin, Lawrence F Bielak, Alanna C Morrison, Sharon L R Kardia, Patricia A Peyser, James E Hixson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3789744?pdf=render

Internet

http://europepmc.org/articles/PMC3789744?pdf=render

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