Malian adults maintain serologic responses to virulent PfEMP1s amid seasonal patterns of fluctuation

Abstract Plasmodium falciparum erythrocyte membrane protein-1s (PfEMP1s), diverse malaria proteins expressed on the infected erythrocyte surface, play an important role in pathogenesis, mediating adhesion to host vascular endothelium. Antibodies to particular non-CD36-binding PfEMP1s are associated...

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Bibliographic Details
Main Authors: Noah T. Ventimiglia, Emily M. Stucke, Drissa Coulibaly, Andrea A. Berry, Kirsten E. Lyke, Matthew B. Laurens, Jason A. Bailey, Matthew Adams, Amadou Niangaly, Abdoulaye K. Kone, Shannon Takala-Harrison, Bourema Kouriba, Ogobara K. Doumbo, Phillip L. Felgner, Christopher V. Plowe, Mahamadou A. Thera, Mark A. Travassos
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92974-7