Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL
Studies in humans and mice have shown that increased expression of apolipoprotein C-I (apoC-I) results in combined hyperlipidemia with a more pronounced effect on triglycerides (TGs) compared with total cholesterol (TC). The aim of this study was to elucidate the main reason for this effect using hu...
Main Authors: | Jimmy F.P. Berbée, Caroline C. van der Hoogt, Deepa Sundararaman, Louis M. Havekes, Patrick C.N. Rensen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2005-02-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520340633 |
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