Vitamin D deficiency aggravates nephrotoxicity, hypertension and dyslipidemia caused by tenofovir: role of oxidative stress and renin-angiotensin system.

Vitamin D deficiency aggravates nephrotoxicity, hypertension and dyslipidemia caused by tenofovir: role of oxidative stress and renin-angiotensin system.

Vitamin D deficiency (VDD) is prevalent among HIV-infected individuals. Vitamin D has been associated with renal and cardiovascular diseases because of its effects on oxidative stress, lipid metabolism and renin-angiotensin-aldosterone system (RAAS). Tenofovir disoproxil fumarate (TDF), a widely use...

Full description

Bibliographic Details
Main Authors: Daniele Canale, Ana Carolina de Bragança, Janaína Garcia Gonçalves, Maria Heloisa Massola Shimizu, Talita Rojas Sanches, Lúcia Andrade, Rildo Aparecido Volpini, Antonio Carlos Seguro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4105615?pdf=render

Internet

http://europepmc.org/articles/PMC4105615?pdf=render

Similar Items