Self-assembled PEGylated albumin nanoparticles (SPAN) as a platform for cancer chemotherapy and imaging

Self-assembled PEGylated albumin nanoparticles (SPAN) as a platform for cancer chemotherapy and imaging

Paclitaxel (PTX) is used as a major antitumor agent for the treatment of recurrent and metastatic breast cancer. For the clinical application of PTX, it needs to be dissolved in an oil/detergent-based solvent due to its poor solubility in an aqueous medium. However, the formulation often causes unde...

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Bibliographic Details
Main Authors: Jung Eun Lee, Myung Goo Kim, Yeon Lim Jang, Min Sang Lee, Nak Won Kim, Yue Yin, Jong Han Lee, Su Yeon Lim, Ji Won Park, Jaeyun Kim, Doo Sung Lee, Sun Hwa Kim, Ji Hoon Jeong
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
drug dissolution
oil-free formulation
human serum albumin
self-assembled nanoparticle
systemic cancer therapy
Online Access:http://dx.doi.org/10.1080/10717544.2018.1489430

Internet

http://dx.doi.org/10.1080/10717544.2018.1489430

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