Controlled Human Malaria Infection Induces Long-Term Functional Changes in Monocytes

Controlled Human Malaria Infection Induces Long-Term Functional Changes in Monocytes

Innate immune memory responses (also termed “trained immunity”) have been described in monocytes after BCG vaccination and after stimulation in vitro with microbial and endogenous ligands such as LPS, β-glucan, oxidized LDL, and monosodium urate crystals. However, whether clinical infections are als...

Full description

Bibliographic Details
Main Authors: Jona Walk, Farid Keramati, L. Charlotte J. de Bree, Rob J. W. Arts, Bas Blok, Mihai G. Netea, Hendrik G. Stunnenberg, Robert W. Sauerwein
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Molecular Biosciences
Subjects:
malaria
trained immunity
epigenetics
RNA-seq
ChIP-seq
CHMI
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.604553/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2020.604553/full

Similar Items