NFAT5 is activated by hypoxia: role in ischemia and reperfusion in the rat kidney.

NFAT5 is activated by hypoxia: role in ischemia and reperfusion in the rat kidney.

The current hypothesis postulates that NFAT5 activation in the kidney's inner medulla is due to hypertonicity, resulting in cell protection. Additionally, the renal medulla is hypoxic (10-18 mmHg); however there is no information about the effect of hypoxia on NFAT5. Using in vivo and in vitro...

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Bibliographic Details
Main Authors: Sandra Villanueva, Cristian Suazo, Daniela Santapau, Francisco Pérez, Mariana Quiroz, Juan E Carreño, Sebastián Illanes, Sergio Lavandero, Luis Michea, Carlos E Irarrazabal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3388090?pdf=render

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http://europepmc.org/articles/PMC3388090?pdf=render

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