Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie’s Disease

Purpose: To examine the therapeutic effect of Vactosertib, a small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor (activin receptor-like kinase-5, ALK5), in an experimental model of Peyronie’s disease (PD) and determining anti-fibrotic mechanisms of Vactosertib in prima...

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Main Authors: Kang-Moon Song, Doo Yong Chung, Min Ji Choi, Kalyan Ghatak, Nguyen Nhat Minh, Anita Limanjaya, Mi-Hye Kwon, Jiyeon Ock, Guo Nan Yin, Dae-Kee Kim, Ji-Kan Ryu, Jun-Kyu Suh
Format: Article
Language:English
Published: Korean Society for Sexual Medicine and Andrology 2020-10-01
Series:The World Journal of Men's Health
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