Ketamine rapidly reverses stress-induced impairments in GABAergic transmission in the prefrontal cortex in male rodents

Ketamine rapidly reverses stress-induced impairments in GABAergic transmission in the prefrontal cortex in male rodents

Dysfunction of medial prefrontal cortex (mPFC) in association with imbalance of inhibitory and excitatory neurotransmission has been implicated in depression. However, the precise cellular mechanisms underlying this imbalance, particularly for GABAergic transmission in the mPFC, and the link with th...

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Bibliographic Details
Main Authors: Sriparna Ghosal, Catharine H. Duman, Rong-Jian Liu, Min Wu, Rosemarie Terwilliger, Matthew J. Girgenti, Eric Wohleb, Manoela V. Fogaca, Emily M. Teichman, Brendan Hare, Ronald S. Duman
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Neurobiology of Disease
Subjects:
Chronic stress
Depression
Somatostatin
Prefrontal cortex
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119303444

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http://www.sciencedirect.com/science/article/pii/S0969996119303444

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