Is there a link between IL-23/IL-17 and developmental pathways such as the Wnt and Hedgehog pathway?

Recent experimental evidence suggests that IL-23 may induce spondyloarthropathy by acting on entheseal resident “innate-like” T cells. These cells express IL-23R and respond to IL-23 by secreting inflammatory cytokines such as IL-6 and IL-17 as well as IL-22 which acts on osteoblasts and regulates b...

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Bibliographic Details
Main Authors: Nicholas Stamatis-Liossis, Dimitrios Daoussis
Format: Article
Language:English
Published: PCO Convin S.A. 2017-01-01
Series:Mediterranean Journal of Rheumatology
Subjects:
wnt
Online Access:https://www.mjrheum.org/assets/files/792/file65_961.pdf