Is there a link between IL-23/IL-17 and developmental pathways such as the Wnt and Hedgehog pathway?
Recent experimental evidence suggests that IL-23 may induce spondyloarthropathy by acting on entheseal resident “innate-like” T cells. These cells express IL-23R and respond to IL-23 by secreting inflammatory cytokines such as IL-6 and IL-17 as well as IL-22 which acts on osteoblasts and regulates b...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
PCO Convin S.A.
2017-01-01
|
Series: | Mediterranean Journal of Rheumatology |
Subjects: | |
Online Access: | https://www.mjrheum.org/assets/files/792/file65_961.pdf |