Embryonic Fibroblasts Promote Antitumor Cytotoxic Effects of CD8+ T Cells

Adoptive CD8+ T cell therapy has emerged as an important modality for the treatment of cancers. However, the significant drawback of transfused T cells is their poor survival and functionality in response to tumors. To overcome this limitation, an important consideration is exploring a culture condi...

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Bibliographic Details
Main Authors: Yingyu Qin, Jung Hoon Shin, Jeong-Ho Yoon, Se-Ho Park
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00685/full