Dystrophic calcifications and Raynaud’s phenomenon in an eight-year old girl
Introduction. Dystrophic calcifications are the most common subtype of skin calcinosis. Tumorous soft tissue calcium deposits usually contain hydroxyapatite and amorphous calcium phosphate. Differential diagnosis of skin calcinosis encompasses Thibierge-Weissenbach syndrome, systemic scl...
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doaj-dddd890f57af4f5f80a97925b0554bca2021-01-02T09:14:31ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792014-01-011423-423924210.2298/SARH1404239G0370-81791404239GDystrophic calcifications and Raynaud’s phenomenon in an eight-year old girlGrebeldinger Slobodan P.0Tomić Jelena M.1Vijatov-Đurić Gordana V.2Radojčić Branka S.3Vučković Nada M.4Ćulafić Jelena N.5Clinic of Pediatric Surgery, Institute for Children and Youth Health Care of Vojvodina, Novi SadPediatric Clinic, Institute for Children and Youth Health Care of Vojvodina, Novi SadPediatric Clinic, Institute for Children and Youth Health Care of Vojvodina, Novi SadClinic of Pediatric Surgery, Institute for Children and Youth Health Care of Vojvodina, Novi SadCenter for Pathology and Histology, Clinical Center of Vojvodina, Novi SadFaculty of Medicine, Novi SadIntroduction. Dystrophic calcifications are the most common subtype of skin calcinosis. Tumorous soft tissue calcium deposits usually contain hydroxyapatite and amorphous calcium phosphate. Differential diagnosis of skin calcinosis encompasses Thibierge-Weissenbach syndrome, systemic sclerosis, scleroderma, CREST syndrome (calcinosis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia), dermatomyositis, systemic lupus erythematosus, ad myositis ossificans progressiva. Case Outline. We present the case of an eight-year old girl with tumorous soft tissue calcium deposits and Raynaud’s phenomenon. At the age of 3.5 years, our patient was admitted to Pediatric Surgery Clinic because of bilateral acrocyanosis localized at the fingertips area of hands, with the signs of vascular trauma. Therapy with vasodilators and hyperbaric oxygen treatment were completed. This therapy resulted in improvement. At the age of eight, the patient was admitted again due to intermittent, painful cramps localized in both hands. Punctiform deposits were present at the tips of fingers and toes, which looked like calcifications and were spontaneously eliminated, with the remnants of crater-shaped defects. A hard tumorous deformity localized in soft tissue was present in the extensor area of the right elbow. Laboratory indicators of inflammation were within the reference values, and antinuclear antibodies were positive. A nodus localized at the right elbow was extirpated. Pathohistological findings: connective and fat tissue with large deposits of calcium. Conclusion. Further follow-up of our patient is necessary due to possible development of complete picture of CREST syndrome or systemic sclerosis.http://www.doiserbia.nb.rs/img/doi/0370-8179/2014/0370-81791404239G.pdfRaynaud diseasecalcinosischild |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Grebeldinger Slobodan P. Tomić Jelena M. Vijatov-Đurić Gordana V. Radojčić Branka S. Vučković Nada M. Ćulafić Jelena N. |
spellingShingle |
Grebeldinger Slobodan P. Tomić Jelena M. Vijatov-Đurić Gordana V. Radojčić Branka S. Vučković Nada M. Ćulafić Jelena N. Dystrophic calcifications and Raynaud’s phenomenon in an eight-year old girl Srpski Arhiv za Celokupno Lekarstvo Raynaud disease calcinosis child |
author_facet |
Grebeldinger Slobodan P. Tomić Jelena M. Vijatov-Đurić Gordana V. Radojčić Branka S. Vučković Nada M. Ćulafić Jelena N. |
author_sort |
Grebeldinger Slobodan P. |
title |
Dystrophic calcifications and Raynaud’s phenomenon in an eight-year old girl |
title_short |
Dystrophic calcifications and Raynaud’s phenomenon in an eight-year old girl |
title_full |
Dystrophic calcifications and Raynaud’s phenomenon in an eight-year old girl |
title_fullStr |
Dystrophic calcifications and Raynaud’s phenomenon in an eight-year old girl |
title_full_unstemmed |
Dystrophic calcifications and Raynaud’s phenomenon in an eight-year old girl |
title_sort |
dystrophic calcifications and raynaud’s phenomenon in an eight-year old girl |
publisher |
Serbian Medical Society |
series |
Srpski Arhiv za Celokupno Lekarstvo |
issn |
0370-8179 |
publishDate |
2014-01-01 |
description |
Introduction. Dystrophic calcifications are the most common subtype of skin
calcinosis. Tumorous soft tissue calcium deposits usually contain
hydroxyapatite and amorphous calcium phosphate. Differential diagnosis of
skin calcinosis encompasses Thibierge-Weissenbach syndrome, systemic
sclerosis, scleroderma, CREST syndrome (calcinosis, Raynaud’s phenomenon,
esophageal dysmotility, sclerodactyly and telangiectasia), dermatomyositis,
systemic lupus erythematosus, ad myositis ossificans progressiva. Case
Outline. We present the case of an eight-year old girl with tumorous soft
tissue calcium deposits and Raynaud’s phenomenon. At the age of 3.5 years,
our patient was admitted to Pediatric Surgery Clinic because of bilateral
acrocyanosis localized at the fingertips area of hands, with the signs of
vascular trauma. Therapy with vasodilators and hyperbaric oxygen treatment
were completed. This therapy resulted in improvement. At the age of eight,
the patient was admitted again due to intermittent, painful cramps localized
in both hands. Punctiform deposits were present at the tips of fingers and
toes, which looked like calcifications and were spontaneously eliminated,
with the remnants of crater-shaped defects. A hard tumorous deformity
localized in soft tissue was present in the extensor area of the right elbow.
Laboratory indicators of inflammation were within the reference values, and
antinuclear antibodies were positive. A nodus localized at the right elbow
was extirpated. Pathohistological findings: connective and fat tissue with
large deposits of calcium. Conclusion. Further follow-up of our patient is
necessary due to possible development of complete picture of CREST syndrome
or systemic sclerosis. |
topic |
Raynaud disease calcinosis child |
url |
http://www.doiserbia.nb.rs/img/doi/0370-8179/2014/0370-81791404239G.pdf |
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