Development and Physicochemical Characterization of Sirolimus Solid Dispersions Prepared by Solvent Evaporation Method

Purpose: The aim of the present investigation was preparation and characterization of sirolimus solid dispersions by solvent evaporation technique to improve its dissolution properties. Methods: Polyvinylpyrrolidone (PVP), Poloxamer 188 and Cremophore RH40 were used to prepare the solid dispersions...

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Bibliographic Details
Main Authors: Shahram Emami, Hadi Valizadeh, Ziba Islambulchilar, Parvin Zakeri-Milani
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2014-12-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-4-369.pdf