Targeting Catecholaminergic Systems in Transgenic Rats With a CAV-2 Vector Harboring a Cre-Dependent DREADD Cassette

Targeting Catecholaminergic Systems in Transgenic Rats With a CAV-2 Vector Harboring a Cre-Dependent DREADD Cassette

Techniques that allow the manipulation of specific neural circuits have greatly increased in the past few years. DREADDs (Designer receptors exclusively activated by designer drugs) provide an elegant way to manipulate individual brain structures and/or neural circuits, including neuromodulatory pat...

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Bibliographic Details
Main Authors: Juan-Carlos Cerpa, Alain R. Marchand, Yoan Salafranque, Jean-Rémi Pape, Eric J. Kremer, Etienne Coutureau
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
DREADD
CAV-2
orbitofrontal cortex
striatum
dopamine
noradrenaline
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00121/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2020.00121/full

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