Mildly Increased Renin Expression in the Absence of Kidney Injury in the Murine Transverse Aortic Constriction Model

Mildly Increased Renin Expression in the Absence of Kidney Injury in the Murine Transverse Aortic Constriction Model

Cardiorenal syndrome type 2 is characterized by kidney failure as a consequence of heart failure that affects >50% of heart failure patients. Murine transverse aortic constriction (TAC) is a heart failure model, where pressure overload is induced on the heart without any systemic hypertension...

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Bibliographic Details
Main Authors: Marian Wesseling, Eva Mulder, Maike A. D. Brans, Daniek. M. C. Kapteijn, Marian Bulthuis, Gerard Pasterkamp, Marianne C. Verhaar, A. H. Jan Danser, Harry van Goor, Jaap A. Joles, Saskia C. A. de Jager
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
transverse aortic constriction
kidney function
cardiorenal syndrome
stroke volume
hypoperfusion
murine (mouse)
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.614656/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.614656/full

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